PAF1 regulation of promoter-proximal pause release via enhancer activation
نویسندگان
چکیده
منابع مشابه
PAF1, a Molecular Regulator of Promoter-Proximal Pausing by RNA Polymerase II
The control of promoter-proximal pausing and the release of RNA polymerase II (Pol II) is a widely used mechanism for regulating gene expression in metazoans, especially for genes that respond to environmental and developmental cues. Here, we identify that Pol-II-associated factor 1 (PAF1) possesses an evolutionarily conserved function in metazoans in the regulation of promoter-proximal pausing...
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ژورنال
عنوان ژورنال: Science
سال: 2017
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.aan3269